The National Institutes of Health (NIH), a part of the U.S. Department of Health and Human Services, is the nation’s medical research agency — making important discoveries that improve health and save lives.
The broad goal of the grant program is to support high-risk, high-impact early discovery research focused on developing vaccine approaches to prevent acquisition of or ongoing infection by HIV. This funding opportunity announcement specifically advocates for a unique Go/No-Go approach to fund high-risk research projects, setting it apart from most R01 projects. Success in the initial stages, as assessed by meeting pre-negotiated Go/No-Go criteria by the end of the second year, is crucial for continued funding throughout the full award duration.